Available until February 1, 2026

As clinicians, we’re used to obtaining health information from our patients through a medical history, performing a physical exam and ordering a variety of lab tests or imaging studies. We then formulate a differential diagnosis and eventually a diagnosis to explain the patient’s health problem. But what happens when a diagnosis isn’t obvious or we’re uncertain what may be causing the patient’s problems. What if a patient asks us a question and we don’t know the answer? How do we express our uncertainty to our patients and how do our patients react to our uncertainty? In this podcast, we’ll discuss diagnostic uncertainty and how to approach our patients when we can’t find a specific diagnosis to explain their symptoms. Our guests include Liz A. Gilman, M.D., and Chris R. Stephenson, M.D., M.H.P.E., both from the Division of General Internal Medicine at the Mayo Clinic.

Available until March 5, 2026 - Online CME Course

Mayo Clinic's Ophthalmology Grand Rounds has been repurposed as an online offering for ophthalmologists, optometrists, physicians, physician assistants, nurse practitioners and nurses who are interested in learning more about a variety of medical and surgical conditions in ophthalmology.

Available until March 5, 2026 - Online CME Course

Mayo Clinic's Ophthalmology Grand Rounds has been repurposed as an online offering for ophthalmologists, optometrists, physicians, physician assistants, nurse practitioners and nurses who are interested in learning more about a variety of medical and surgical conditions in ophthalmology.

Available until March 5, 2026 - Online CME Course

Mayo Clinic's Ophthalmology Grand Rounds has been repurposed as an online offering for ophthalmologists, optometrists, physicians, physician assistants, nurse practitioners and nurses who are interested in learning more about a variety of medical and surgical conditions in ophthalmology.

Available until February 1, 2026

It’s estimated that C. difficile causes about a half million infections each year in the U.S. and 1 in 6 of those will have a recurrence within a couple months. Although C. difficile typically occurs following the use of antibiotics, it can also be spread from one individual to another, especially in hospitals and skilled nursing facilities. What are the common symptoms of an infection with C. difficile? How do we test for it? How should an infection be treated and what do we do with patients who have one or more recurrences. In this podcast, we’ll be discussing “What’s New with C. Difficile?” and these are some of the questions I’ll be asking our guest, Sahil Khanna, M.B.B.S., M.S., a gastroenterologist from the Mayo Clinic.

Available until February 1, 2026

Among adolescents, complaints regarding fatigue are relatively common and it’s been assumed to be associated with the hormonal changes of puberty, the various social conflicts common in adolescence and a variety of educational expectations. At times, fatigue becomes chronic and may be accompanied by other physical symptoms including mood disorders, headaches, musculoskeletal pains, and various GI symptoms. When chronic fatigue in adolescence has been investigated, no single causal factor has been found and its likely to be multi-factorial. The topic for this podcast is “Chronic Fatigue in Adolescents” and we’ll discuss this with our guest Philip R. Fischer, M.D., a pediatrician from the Department of Pediatrics at the Mayo Clinic.

Available until September 17, 2026 - Online CME Course

This online course features evidence-based and cutting-edge diagnostic and treatment strategies for sports-related and musculoskeletal hip injuries and conditions. The content is multidisciplinary, including anatomy, radiology, non-operative and operative management of these conditions.